IMPACT OF ROBUST TREATMENT PLANNING ON SINGLE- AND MULTI-FIELD OPTIMIZED PLANS FOR PROTON BEAM THERAPY OF UNILATERAL HEAD AND NECK TARGET VOLUMES

Impact of robust treatment planning on single- and multi-field optimized plans for proton beam therapy of unilateral head and neck target volumes

Abstract Background Proton beam therapy is promising for the treatment of head and neck cancer (HNC), but it is sensitive to uncertainties in patient positioning and particle range.Studies have shown that the planning target volume (PTV) concept may not be sufficient to ensure robustness of the target coverage.A few planning studies have considered

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Plasmodium infection inhibits tumor angiogenesis through effects on tumor-associated macrophages in a murine implanted hepatoma model

Abstract Background Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death in China.The lack of an effective treatment for this disease results in a high recurrence rate in patients who undergo radical tumor resection, and the 5-year survival rate of these patients remains low.Our previous studies demonstrated that Plas

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